Abstract
Materials and methods All inborn ELBW neonates admitted to our NICU during a 5-year period were eligible for this retrospective analysis. Exclusion criteria were: birth weight (BW) 240 mg/dL in a single determination or >180 mg/dL in two determinations at 2-hour intervals. Continuous intravenous insulin infusion was started after an ineffective glucose restriction.
Highlights
Glucose metabolism disorders are common in extremely low birth weight (ELBW) infants and are associated with high morbidity and mortality [1-9]
Hypoglycemia was defined as blood glucose level (BGL) ≤45 mg/dL; hyperglycemia as BGL>240 mg/dL in a single determination or >180 mg/dL in two determinations at 2-hour intervals
Normoglycemia was observed in neonates (47.6%) (N-Group); neonates (52.4%) showed abnormal BGL: 21 (12.7%) were hypoglycemic (Hypo-Group), 53 (31.9%) hyperglycemic (Hyper-Group) and 13 (7.8%) showed both hypoglycemia and hyperglycemia (Hypo&Hyper-Group)
Summary
Glucose metabolism disorders are common in extremely low birth weight (ELBW) infants and are associated with high morbidity and mortality [1-9]. This study was conducted to evaluate the prevalence and risk factors associated with both hypo and hyperglycemia in ELBW infants
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