Hypoglycaemic study of some umbelliferae seeds in albino rats

Abstract

Blood glucose levels were determined in normal, glucose loaded (hyperglycaemic) and diabetic rats after oral administration of some of the Caraway species and allied seeds (Cuminum Cyminum, Carum bulbocastanum, Carum Carvi, Trachyspermum ammi, and Cuminum nigrum). The data showed that the aqueous suspension of Carum Carvi seeds caused a significant reduction in blood glucose level in normoglycaemic, hyperglycaemic as well as alloxanated diabetic rats. The, drug however, did not show any blood glucose lowering effect in streptozotocin treated rats. It is suggested that C. Carvi, seeds have some hypoglycaemic principle.