Hypoglycaemia due to Autoimmunity

Abstract

Hirata disease is an insulin autoimmune disease characterized by non-exogenous hyper insulinemic postprandial hypoglycemia due to elevated insulin autoimmune antibodies (IAS), with no exogenous insulin and no pathological abnormalities of pancreatic islets cells, the diagnosis is often missed due to the rarity of the disease, failure to diagnose Hirata disease in a timely manner often results in exposing the patients to unnecessary investigation and surgical procedures.