Abstract
Ancient medicine, characterized by great observation, attached great importance to the reactivity of the body in the occurrence of various diseases. Already then, Ptolemy Dioscorides and Sextus Empiricus spoke of idiosyncrasies, and Galen introduced the doctrine of idiopathies. In subsequent periods, this question has always received attention and has never been so ignored as at the end of the last century, when in connection with the blossoming of microbiology they looked for the cause of the different course of diseases in the character of the biological properties of the microorganism, while forgetting the individual characteristics of the organism itself.
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