Hypo- versus hyper-thyroidism in 2 cats: the culprit for miliary dermatitis/hypersensitivity versus growth retardation

Songül Erdoğan,Hasan Erdoğan,Kerem Ural

doi:10.24998/maeusabed.655058

Abstract

In the present case series 2 different cats with diagnosis of hypo- versus hyper-thyroidism with distinct clinical signs were reported. The first case was a 3-month-old male domestic short-hair kitten was presented with a disproportionate dwarfism. Radiographic examination of the long bones revealed epiphyseal dysgenesis and delayed epiphyseal ossification. Congenital primary hypothyroidism was established by low serum total thyroxine. Initial treatment composed of levothyroxine. The second case was referred to the clinic with unresolved dermatological problems. On referral alopecia, extensive crusting and matting of the haircoat were evident. Hyperthyroidism and related military dermatitis was detected based on elevated serum total thyroxine and free T4 levels along with skin punch biopsy results. Therapeutical armamentarium composed of methimazole and hyperimmune milk factor. Early recognition, diagnosis and treatment intervention all resulted in clinical remission and relief of clinical signs accompanied by normal thyroidal function and laboratory results in both cats.

Highlights

Hyperthyroidism, one of the most frequent endocrine disorder in middle to older aged cats (Peterson, 1986; Feldman and Nelson, 1996; Hibbert, 2018), denote excessive production of thyroid hormones due to abnormally functioning thyroidal tissue (Volckaert et al, 2016a)
Congenital hypothyroidism in cats is a rare disorder resulting with disproportionate dwarfism (Scott-Moncrieff, 2007; Johnson and Watson, To cite this article: Erdoğan S, Ural K, Erdoğan H. (2019)
The owner informed that the cat was not playing with toys or its brother belonging to the same litter

Summary

Introduction

Hyperthyroidism, one of the most frequent endocrine disorder in middle to older aged cats (Peterson, 1986; Feldman and Nelson, 1996; Hibbert, 2018), denote excessive production of thyroid hormones due to abnormally functioning thyroidal tissue (Volckaert et al, 2016a). Congenital hypothyroidism in cats is a rare disorder resulting with disproportionate dwarfism Hypo- versus Hyper-thyroidism in 2 Cats: The Culprit for Miliary Dermatitis/Hypersensitivity Versus Growth Retardation. Growth retardation, altered mental status, neuromuscular deficits, retention of hair coat, and other relevant signs might be detected in hypothyroid kittens (Feldman and Nelson, 2004; Scott-Moncrieff 2007; Szabo and Wells, 2007; Pettigrew et al, 2007; Johnson and Watson, 2010; Quante et al, 2010; Bojanic et al, 2011). The present author’s interest was aroused following receipt of two different cats, 1 with hypo- and the other with hyper-thyroidism with specifical clinical findings and treatment

Case Report

Available data

Findings

Discussion