Abstract
This review is focused on the hypothesis that hypnosis can differentially modulate T-cell subsets and that this effect is mediated by changes in hypothalamo-pituitary-adrenal (HPA) mediators, such as cortisol. Psychoneuroimmunology (PNI) is the study of the interaction between psychological processes and the nervous and immune systems, taking an interdisciplinary approach including psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology and rheumatology. The main interests of this discipline are the interactions between the nervous and immune systems studying mental processes leading to pathologies due to auto-immunity or immune deficiency. Here we make an overview about history of PNI focusing on hypnosis as a modulator of immune response and a therapeutic tool to heal stress related diseases. Here we also share our ideas about studying clinical use of cortisol as a reliable monitor for hypnosis therapy on the homeostasis of hypothalamic-pituitary-adrenal axis (HPA axis).
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