HYPERURICEMIA IN PATIENTS WITH HYPERTENSION AND OBESITY: PREVALENCE AND CORRELATIONS WITH METABOLIC SYNDROME

Abstract

Objective: Describe hyperuricemia prevalence in people diagnosed with hypertension and obesity attended in a Hypertension ambulatory and co-related the metabolic syndrome with hyperuricemia. Design and method: A retrospective cross-sectional study in which data comes from patients’ electronic medical records watched between January 2018 to December 2019 in a Cardiovascular Hospital in Sao Paulo, Brazil. Sex, age, arterial systolic and diastolic blood pressure, abdominal circumference, uric acid, fasting glycemia, HDL-c, and triglycerides were collected from the latest result during that period. The National Cholesterol Education Program's Adult Treatment Panel III (NCEP-ATP III) as a reference to metabolic syndrome definition. Pearson and Spearman correlation test to describe the correlation between uric acid and metabolic syndrome requirements, according to p < 0.05 as a statistical significance. Results: 31 patients watched with 54 ± 11 years old; most were women (64,5% n = 20). In addition, 45,2% (n = 14) shows hypertension diagnostics and all had metabolic syndrome. It was observed linear positive correlation between uric acid values and abdominal circumference (r = 0,493; p = 0,005), triglycerides (r = 0,467; p = 0,008). It was not found correlation between glycemia (r = 0,202; p = 0,276), SBP (r = 0,295; p = 0,107), DBP (r = 0,273; p = 0,335) and HDL-c (r = 0,194; p = 0,295). Conclusions: Hyperuricemia is prevalent between individuals’ diagnostics with hypertension and obesity, and also shows relation with metabolic syndrome, introducing the importance of the nutritional actions to prevent and minimize hypertension and obesity-associated, including the acid uric diet control.