Abstract
Aim. To study the prevalence of hyperuricemia in the Russian regions, depending on the climatic, geographical, socio-demographic characteristics and some cardiometabolic risk factors. Material and methods. Data from the ESSE-RF study from 10 regions of theRussian Federationare presented. All study participants were examined according to a uniform protocol. Measurements were standardized, biochemical tests were carried out in three Federal centers using the same methodology. The study was approved by independent Ethics committees, and all participants signed informed consent. Results. The prevalence of hyperuricemia was 16.8% (25.3% in men and 11.3% in women; p<0.0001). Hyperuricemia incidence increases with age, does not depend on education, significantly associates with place of residence, elevated blood pressure, obesity and abdominal obesity, alcohol consumption and diuretics taking. After adjustment for all factors included in the regression analysis, prevalence of hyperuricemia in the Ivanovo Region is 1.4 times higher than this in the reference region (Tyumen), while prevalence of hyperuricemia in the Samara Region and theRepublicofNorth Ossetia-Alaniais 30% and 40 % lower. Conclusion. Prevalence of hyperuricemia inRussiais defined; regions with the highest and lowest prevalence are identified. Associations of hyperuricemia with some social and demographic characteristics as well as cardiovascular risk factors are revealed.
Highlights
After adjustment for all factors included in the regression analysis, prevalence of hyperuricemia in the Ivanovo Region is 1.4 times higher than this in the reference region (Tyumen), while prevalence of hyperuricemia in the Samara Region and the Republic of North Ossetia-Alania is 30% and 40 % lower
Conen D, Wietlisbach V, Bovet P, et al Prevalence of hyperuricemia and relation of serum uric acid with cardiovascular risk factors in a developing country.BMC Public Health 2004; 25: 4-9
Summary
Изучить распространенность гиперурикемии в регионах России в зависимости от климато-географических, социально-демографических показателей и некоторых кардиометаболических факторов риска Материал и методы. Установлена ассоциация гиперурикемии с рядом социально-демографических показателей и факторов сердечно-сосудистого риска. 10, Moscow, 101990 Russia 2Research Institute for Complex Issues of Cardiovascular Diseases under the Siberian Branch of the Russian Academy of Medical Sciences. 22, Ivanovo, 153012 Russia 10North Ossetia State Medical Academy. 40, Vladikavkaz, North Ossetia-Alania Republic, 362007 Russia 11Research Institute for Cardiology under the Siberian Branch of the Russian Academy of Medical Sciences. Недостаточно данных, доказывающих, что снижение уровня МК приведет к предупреждению, или, по крайней мере, замедлению процесса формирования компонентов метаболического синдрома, диабета, заболеваний почек или снижению сердечно-сосудистых осложнений. По Российским регионам таких данных не имеется, поэтому целью настоящей работы является изучение распространенности ГУ в зависимости от климато-географических, социально-демографических показателей и некоторых кардиометаболических факторов риска
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