Abstract
Hyperthyrotropinemia Prevalence and Metabolic Syndrome Estimates in Elders in a Formerly Endemic Goiter Area
Highlights
Thyrotrophic hormone levels reflect thyroid function [1]
SH was positively associated with high thyroid peroxidase antibodies (TPOAb), HTN, DL treatment, High Total Cholesterol (HtCh), and symptoms, 27.0% vs 3.8%, χ2=23.1 P
SH was indifferent to gender, oldest old, high Triglycerides (TG), Low High-Density-Lipoproteins (HDL), diabetes; but Logistic Regression (LR) showed SH inversely associated to HDL, and HbA1c, and directly associated to symptoms, HTN and HtCh, all P
Summary
Hallowell reported that 4.2% of Mexican-Americans 12 years of age or older have thyrotrophic hormone (TSH) levels>4.5 μIU/mL. In disease-free individuals 70-79 years of age, elevated thyroid peroxidase antibodies (TPOAb) were present in 21.8%. In these increased TSH reaches 12%; if TPOAb positive subjects are excluded it only reaches 6% [2]. Hypothyroidism prevalence varies according to environmental and genetic factors [1]. Hypothyroid symptoms may be obscured by concomitant morbidities and/or confused by changes in aging [3,4]. Damage to target tissues by subclinical hypothyroidism has been documented [5,6]
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