Abstract
The thyroid, as one of the glands of internal secretion to be studied first and subsequently most intensively, was early regarded with interest in relation mental disorder. Its role in the production of cretinism and in myxoedema in which the activity of the gland is diminished, as well as the association of thyrotoxicosis with psychic changes, suggested that anomalies of this organ might be linked with some forms of mental disease.
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