Abstract
Hyperthyroidism remains the most commonly diagnosed endocrinopathy in older cats. Measurement of total thyroxine (tT4) is diagnostic in most cases, but results within the reference interval may be obtained in cats with early hyperthyroidism and those with concurrent disease. Further thyroid function testing may include measurement of free thyroxine and thyroid stimulating hormone, or re-testing tT4 after 4 weeks. Chronic kidney disease is a common comorbidity and both diseases should be optimally managed, including definitive treatment of hyperthyroidism if indicated. Iatrogenic hypothyroidism may occur whatever treatment modality is used and, given the association with azotaemia and a poorer prognosis, should be treated with thyroxine.
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