Abstract

In het eerste deel van dit overzichtsartikel worden de schildklieranatomie, fysiologie en pathofysiologie bij katten besproken. Vervolgens wordt de nadruk gelegd op hyperthyreoïdie, de meest voorkomende schildkliergerelateerde aandoening bij katten. De diagnosestelling wordt verder besproken met nadruk op de medische beeldvorming. Scintigrafie is veruit de meest gebruikte en geschikte techniek om de schildklierfunctie te evalueren. Daarop wordt in het tweede deel van dit overzichtsartikel dieper ingegaan. Andere beeldvormingsmodaliteiten bieden geen evaluatie van de schildklierfunctie en zijn daarom van minder belang voor de diagnose en evaluatie van hyperthyreoïdie.

Highlights

  • THYROID GLAND ANATOMYThe thyroid glands are two small elongated structures, located caudal to the larynx and lateral to the trachea on each side (Figures 1 and 2)

  • In the first part of this review article, thyroid anatomy, physiology and pathophysiology are reviewed to continue on hyperthyroidism, the most common thyroid disorder in cats

  • Little islets of thyroid cells can separate from the thyroidal primordium and become incorporated in developing structures of the thorax and brachial arch region due to this close relationship with the developing aortic sac

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Summary

THYROID GLAND ANATOMY

The thyroid glands are two small elongated structures, located caudal to the larynx and lateral to the trachea on each side (Figures 1 and 2). Little islets of thyroid cells can separate from the thyroidal primordium and become incorporated in developing structures of the thorax and brachial arch region due to this close relationship with the developing aortic sac. These islets will form foci of ectopic thyroid tissue (Capen, 2007; Lynn et al, 2009; Dyce et al, 2010a; Dyce et al, 2010b; De Felice and Di Lauro, 2011; Peterson and Broome, 2015). They will activate lipoprotein lipase and create an increase sensitivity of the adipose tissue to lipolysis, regulated by other hormones They increase the conversion of cholesterol into bile acids and other substances. Thyroid hormones are responsible for the development of the nervous system in young animals and normal growth and development in cooperation with growth hormone (Capen, 2007; Klein, 2012b)

FELINE HYPERTHYROIDISM
Diagnosis of hyperthyroidism
Clinical features
Blood Tests
THYROID GLAND IMAGING
Computed tomography
Magnetic resonance imaging
Findings
CONCLUSION
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