Abstract

Background: Prognosis for pancreatic cancer remains very poor, and has scarcely improved over the last two decades, with a 5-year overall survival of less than 10%. The only curative option is surgery, which is recommended when full resection of the tumor is possible. In cases of borderline resectable cancer, conventional cytotoxic chemotherapy is used to try to shrink the tumor in order to increase the chance of removing the whole tumor. To improve outcome, hyperthermia (HT) treatment has been suggested as a sensitizer to standard of care therapies.

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