Abstract

Purpose: To report a masquerade syndrome secondary to multiple myeloma iris infiltration.Design: Observational case report.Methods: A 74-year-old Caucasian woman presenting with unilateral hypertensive uveitis and past medical history significant for multiple myeloma underwent aqueous cytology and a trabeculectomy with iridectomy.Results: Cytology revealed atypical plasma cells in the aqueous while the anatomopathologic analysis of iris tissue demonstrated a substitution of the iris tissue by neoplastic plasma cells. After surgery and a new cycle of chemotherapy best-corrected visual acuity and intraocular pressure improved.Conclusions: Masquerade syndrome should always be considered in elderly uveitis. A correct diagnosis can be life-saving.

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