Abstract
A 10-year-old girl presented with a syndrome characterized by hypertension, hypokalemic alkalosis, and inability of the kidneys to concentrate the urine and conserve potassium. The aldosterone excretion and secretion rate were subnormal to low both when she was on a liberal sodium intake and on restricted sodium intake. Treatment with Triamterene resulted in potassium retention , restoration of normal serum potassium level, abolition of the alkalosis, normalization of the blood pressure, and increase of aldosterone secretion rate. The differential diagnosis in conditions associated with hypokalemic alkalosis and renal wastage of potassium is discussed.
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