Abstract
Tooth hypersensitivity is a common symptom in patients with molar-incisor hypomineralization (MIH). Therefore, this clinical study aimed to assess potential associations between patient- and tooth-related variables and the intensity of hypersensitivity in MIH-affected permanent teeth compared to healthy controls. Fifty-seven MIH patients and 20 healthy adolescents with a total of 350 MIH-affected and 193 healthy teeth were included in this study. The intensity of hypersensitivity was measured after cold air stimulation using the Schiff Cold Air Sensitivity Scale (SCASS) by the dentist and visual analogue scale (VAS) by the patient. Tooth hypersensitivity was low in non-MIH teeth (97.9% of the group had zero SCASS and VAS values). In contrast, MIH-affected teeth with demarcated opacities and atypical restorations had moderate SCASS and VAS values, whereas teeth with enamel breakdown were mostly linked to severe hypersensitivity. The logistic regression model confirmed a significantly lower level of hypersensitivity in MIH patients aged ≥ 8 years (OR 0.06, 95% CI 0.01–0.50, p = 0.009) and higher levels in molar teeth (OR 5.49, 95% CI 1.42–21.27, p = 0.014) and teeth with enamel disintegration (OR 4.61, 95% CI 1.68–12.63, p = 0.003). These results indicate that MIH-related tooth hypersensitivity seems to be present in disintegrated molars immediately after tooth eruption.
Highlights
Tooth hypersensitivity is a common symptom in patients with molar-incisor hypomineralization (MIH)
This clinical study was conducted in accordance with the Declaration of Helsinki and was reported following the Strengthening the Reporting of Observational studies in Epidemiology (STROBE) guidelines for observational studies[22]
A total of 54.6% of the MIH lesions were registered on permanent molars (N = 192) and premolars (N = 14), and 45.4% were identified on incisors (N = 153) and canines (N = 18)
Summary
Tooth hypersensitivity is a common symptom in patients with molar-incisor hypomineralization (MIH) This clinical study aimed to assess potential associations between patient- and toothrelated variables and the intensity of hypersensitivity in MIH-affected permanent teeth compared to healthy controls. The logistic regression model confirmed a significantly lower level of hypersensitivity in MIH patients aged ≥ 8 years (OR 0.06, 95% CI 0.01–0.50, p = 0.009) and higher levels in molar teeth (OR 5.49, 95% CI 1.42–21.27, p = 0.014) and teeth with enamel disintegration (OR 4.61, 95% CI 1.68–12.63, p = 0.003). While hypersensitivity is one of the main symptoms in children with M IH13,19,20, it is surprising that only two author groups have published scientific data on this issue far[18,21] Both groups confirmed the common clinical observation of marked hypersensitivity and reported a proportional increase with increasing MIH severity. The null hypothesis was that there is no difference in hypersensitivity in MIH-affected teeth and healthy teeth
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