Abstract
Since the first discovery of an Ih current in heart pacemaker cells about twenty years ago our knowledge on this ion channel class has increased substantially. Studies from a variety of groups have clearly demonstrated that Ih is not only required for cardiac pacemaking but also is a key regulator of several neuronal functions. The long-sought molecular cloning of the genes underlying Ih has now provided the basis to achieve a deeper understanding of the molecular function and physiological regulation of these channels. In addition, the powerful approaches of mouse genetics will enable us to study the physiological roles of the channels in significantly more detail than it was possible up to now.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Reviews of physiology, biochemistry and pharmacology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
