Abstract
Hemochromatosis results from abnormal, chronic accumulation of iron-containing pigment in body tissues. It may occur as a primary, inherited disease or as a secondary state caused by iron overload from medication or repeated blood transfusions. The typical clinical alterations associated with hemochromatosis are hepatomegaly, heart disease, arthritis, hypogonadism, diabetes mellitus, and skin hyperpigmentation. The latter two alterations account for the appellation, bronze diabetes.l Patients with primary hemochromatosis are best treated byfrequent phlebotomy, but anemic patients with secondary hemochromatosis from frequent blood transfusions are precluded from this therapy.
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