Abstract
Hyperostosis frontalis interna (HFI) is a rare disorder common among postmenopausal females that involve increased volume and porosity of the frontal bone. Depending on the size, it could be symptomatic or asymptomatic. With a little report on the pathophysiology of HFI, we present a peculiar case of HFI with speculations that could shed more light on the already established literature and pose questions for future research.
Highlights
Hyperostosis frontalis interna (HFI) is an abnormal growth of the frontal bone at the anterior part of the skull (1)
It is suggested that HFI is associated with hormonal changes that lead to angiogenesis, causing changes in the frontal bone structure (3)
We present a female cadaver with prominent visible HFI and discuss possible clinical symptoms based on its presentation
Summary
Hyperostosis frontalis interna (HFI) is an abnormal growth of the frontal bone at the anterior part of the skull (1). It is characterized by an increased volume and porosity of the inner and diploe plate of the frontal bone (2). It is suggested that HFI is associated with hormonal changes that lead to angiogenesis, causing changes in the frontal bone structure (3). Previous studies have suggested various probable causes of HFI and associated symptoms (5-7), but these are rather speculative, and further studies and experimental evidence are needed for a solid conclusion. We present a female cadaver with prominent visible HFI and discuss possible clinical symptoms based on its presentation.
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