Abstract
SummaryHyperkalaemic periodic paralysis (HYPP) is a relatively new genetic disease that, so far, appears to be confined to descendants of the American Quarter Horse Impressive, a stallion identified as the link between the pedigrees of all affected horses, and that predominantly affects Quarter Horses but also Paint horses, Appaloosas and Palominos. This study suggests that an episode of muscle weakness, which was reported in a Criollo Argentino genetically unrelated to Impressive, was related to marked hyperkalaemia. The symptoms in this case were reproducible following a KCI challenge test although DNA testing for HYPP was negative. Based on these findings, a diagnosis of a HYPP‐like syndrome was made.
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