Abstract
The HVS on FLAIR imaging is a useful marker of acute ischemic stroke. We investigated whether prior administration of gadolinium-based contrast hindered detection of this sign on images from subjects with acute nonlacunar ischemic stroke <4.5 hours after onset. Both blinded and comparative unblinded analyses showed significantly reduced HVS detection on postcontrast images. We suggest that assessment for this sign should be performed on images acquired prior to contrast administration.
Highlights
The detection of HVS by BA in the post- but not precontrast FLAIR imaging occurred in only 2 subjects
Given the potential utility of postcontrast FLAIR images after acute ischemic stroke in clinical and research settings, neuroradiologists and neurologists should be aware of the optimal imaging conditions for detection of the HVS, which include assessment of FLAIR imaging performed before gadolinium-based contrast administration
Gadolinium reduces the detection of the HVS after ischemic stroke
Summary
Our experience in the acquisition of postcontrast FLAIR images suggested that their sensitivity may be less than that in such images acquired before contrast administration. The aim of this study was to determine an effect of gadolinium in the detection of HVS, which we have successfully achieved
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