Abstract
OBJECTIVE: Human chorionic gonadotropin (hCG) is present in seminal plasma (SP) and its concentration correlates with semen analysis (SA) results. We recently confirmed the presence of hCG receptors (hCGR) on sperm and found a correlation with sperm concentration suggesting a role in spermatogenesis. HhCG is an isoform of hCG associated with early embryo implantation and has a longer half-life due to an increased number of glucose residues. It is unknown if this translates into more biological activity.
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