Hyperglycemia‐induced seizures and visual symptoms due to reversible occipital damage: A case series

Abstract

AbstractSeizures associated with hyperglycemia are mostly partial motor with or without secondary generalization. Occipital lobe seizures due to hyperglycemia have been reported in few case studies. The clinical characteristics, electroencephalogram (EEG), and imaging findings of the patients with poorly controlled sugars, visual impairment, and seizures were analyzed. Three patients presented with poorly controlled sugars, seizures, and visual symptoms including visual impairment and occipital seizures over a period of 6 months. EEG showed frequent occipital spikes and electrical seizures of occipital origin. Magnetic resonance imaging brain showed T2 FLAIR hypointensity over the subcortical white matter and gyral changes over the parieto‐occipital area. All of them showed good clinical improvement with antiepileptic medications and good glycemic control. The imaging repeated on follow‐up in two patients showed complete resolution of T2 FLAIR hypointensity. Hyperglycemia‐induced changes can occur with a predeliction for occipital lobe. The visual impairment and occipital seizures respond to glycemic control and anticonvulsants.