Hyperglycemia - an Unexpected Complication in Term Infants with Stage II HIE Treated with Therapeutic Hypothermia (TH) in a Developing Country

Abstract

Purpose: Birth asphyxia and Hypoxic Ischemic Encephalopathy (HIE) are major problems in developing countries such as India. Therapeutic Hypothermia (TH) is well established for treating moderate (Sarnat Stage II) HIE in developed countries but its use in developing countries has raised some concerns (Thayyil, Costello et al. 2009). In October 2015, an Infant Cooling Program was started at the NICE institute in Hyderabad, India using equipment (Blanketrol III) and protocols that were used in the NICHD trials in USA (Shankaran, Laptook et al. 2005). A US team (Connecticut Children’s …