Abstract
Summary: A case is presented of a patient with recurrent peptic ulceration due to an excluded gastric antrum. The patient demonstrated basal hypergastrinaemia and gastric secretory studies showed a high basal acid output with only a slight increase following pentagastrin stimulation. Intravenous secretin injection caused a marked fall in serum gastrin and gastric acid output in this patient. This is in contrast to two patients with Zollinger-Ellison syndrome in whom secretin produced a rise in serum gastrin; and one of these patients who had an intact stomach, also showed a rise in gastric acid output. It is suggested that gastrin and acid output measurement after secretin injection may provide a method of differentiation of an excluded gastric antrum from the Zollinger-Ellison syndrome.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
