Abstract

Introduction: Hypereosinophilic syndrome (HES) is a rare disorder characterised by idiopathic eosinophilia with organ system involvement. Its major tissue target is the heart, assuming diverse aspects that affect its different tunics with a varied clinical and echocardiographic expression. Cardiac involvement is frequently associated with ventricular thrombosis, portending a poor prognosis as it can be complicated by acute embolic events, along with the progressive development of restrictive cardiomyopathy, valvular dysfunction, and heart failure. Case Report: We report the case of a 62 years old woman, who presented one month ago a pulmonary embolism, and was admitted for an ischemic stroke related to a ventricular thrombus in the context of a hypereosinophilia syndrome. Conclusion: Embolic manifestations secondary to cardiac involvement may be a mode of revelation of HES. The mortality related to cardiac damage is high, hence the need for appropriate management.

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