Abstract
The effect of OHP was studied in hemorrhagic and bacteremic shock in dogs. Beneficial effects in hemorrhagic shock occurred only early in the less severe stage of shock. In bacteremic shock, direct exposure of the microorganisms to OHP appears to be necessary for growth inhibition and subsequent improvement in survival. Many problems relating to the correction of oxygen deficits and oxygen poisoning, to have an effect on host mechanisms as well as on microorganisms, require continued and expanded investigation.
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