Abstract
OXYGEN under increased pressure has been used in cardiac surgery1 , 2 and in the treatment of a variety of conditions, including the respiratory-distress syndrome of the newborn infant,3 , 4 anaerobic infections5 and tissue ischemia6 and in the radiotherapy of tumors7 although the efficacy of hyperbaric oxygen in most of these diseases remains to be proved. The principle behind treatment with oxygen under pressure is to produce a high arterial oxygen tension (PaO2 ). The large increase in PaO2 that occurs in hyperbaric oxygen when the circulation is normal has been measured,8 but the influence of venoarterial shunts on . . .
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