Abstract
The urinary steroid pattern was characterized in an 11-yr-old child with congenital adrenal hyperplasia, hypertension, and multiple adrenal rest tumors of the ovaries. Compensated 11β-hydroxylation deficiency was suggested by increased excretion of THS, TH-DOC and 11-desoxy-17-KS, and normal urinary THF and THE, THB, and 11-oxy-17-KS. A previously undescribed abnormality of unusual interest was the finding of increased aldosterone excretion, which fell to normal, as did the blood pressure, with effective adrenal suppression. This finding suggests that increased secretion of aldosterone as well as DOC may contxibute to the hypertension in this form of CAH.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: The Journal of clinical endocrinology and metabolism
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.