Abstract
The urinary steroid pattern was characterized in an 11-yr-old child with congenital adrenal hyperplasia, hypertension, and multiple adrenal rest tumors of the ovaries. Compensated 11β-hydroxylation deficiency was suggested by increased excretion of THS, TH-DOC and 11-desoxy-17-KS, and normal urinary THF and THE, THB, and 11-oxy-17-KS. A previously undescribed abnormality of unusual interest was the finding of increased aldosterone excretion, which fell to normal, as did the blood pressure, with effective adrenal suppression. This finding suggests that increased secretion of aldosterone as well as DOC may contxibute to the hypertension in this form of CAH.
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