Abstract
A saline extract from the fascia of musculus rectus abdominis with increased capacity to aggregate the platelets <i>in vitro</i> was found in two uraemic patients with recurrent obstructive thrombosis frequently complicating the shunts used for haemodialysis, and in five patients with recurrent spontaneous deep venous thrombosis. None of these patients had any other disorder known to predispose to thrombosis. The increased capacity of the fascia extract to induce platelet aggregation may be due to a hitherto unknown cause of thrombosis, namely a defect in the collagen structure or in the subendothelial substances.
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