Abstract

[Hydroxy(tosyloxy)iodo]benzene (HTIB), one of the most significant reagents among the family of hypervalent iodine reagents, has been widely used as an effective ­oxidant in the synthesis of various organic compounds. HTIB was first discovered in 1970 by Neiland and Karele. [1] A few years later, Koser and co-workers discovered that HTIB is an efficient reagent in organic synthesis, so in contemporary literature HTIB is often referred to as ‘Koser’s Reagent’.

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