Abstract
Hydroxyapatite, a naturally occurring form of calcium phosphate, is the main mineral component of bones and teeth. Natural hydroxyapatite and bone have similar physical and chemical characteristics make it biocompatible. Its porous structure resembles native bone. The biocompatibility, biodegradability and bioactivity make it extensively useful in interdisciplinary fields of sciences like chemistry, biology, and medicine. Calcium phosphate-based ceramics are of great interest as substitutes of synthetic bone graft due to their similarities in composition to bone mineral and bioactivity as well as osteoconductivity. This article gives an overview of hydroxyapatite from its preparation and properties to biomedical applications of its composites.
Highlights
Hydroxyapatites (HAP) is a naturally occurring mineral form of calcium apatite comprising of about 50% of the weight of the bone, which accounts for its excellent osteoconductive and osteointegrative properties [1] [2] [3]
This study suggested the feasible use of novel polymer/ceramic composites as scaffold in bone tissue engineering applications [69]
Many investigations have been developed for 3D printing of polymer-ceramic composites, among them polymer-hydroxyapatite composites are of great interest [83] [84]
Summary
Hydroxyapatites (HAP) is a naturally occurring mineral form of calcium apatite comprising of about 50% of the weight of the bone, which accounts for its excellent osteoconductive and osteointegrative properties [1] [2] [3]. It is a main component of bone mineral but in some cases carbonate-apatite is a main hard tissue component, as in dental enamel [4]. This article gives an overview on different ways of hydroxyapatite preparation, its properties and biomedical applications of its composites
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