Abstract
Oxidative stress and bacterial contamination are important causes of titanium implant failure. Although several titanium surface modification techniques have been developed, it is still challenging to combine antioxidant and antibacterial properties. Here, in this study, cerium/zinc-epigallocatechin gallate (EGCG) (ECe&Zn) coatings were constructed on titanium surfaces with antioxidant and antibacterial properties based on metal-polyphenol coating technology and hydrothermal synthesis. SEM and XPS results confirmed the successful preparation of the ECe&Zn coating. Antioxidant experiments showed that Ti-ECe&Zn possessed multiple antioxidant enzyme-like activities and good free radical scavenging ability. In vitro biological evaluation revealed that Ti-ECe&Zn was not cytotoxic and had excellent antibacterial properties. The present work provided a simple and effective method for endowing medical implants with both multiple antioxidant and antibacterial properties.
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