Abstract
AbstractHerein we report the synthesis of three heteroleptic first‐row transition metal(II) complexes containing carbazolido NNN pincer ligands and conversion to the corresponding metal(I)‐carbonyl complexes via a reductive carbonylation route. These complexes are precatalysts for the hydrophosphination of activated alkenes, affording a cobalt‐catalysed hydrophosphination process that solely and selectively yields the β addition (anti‐Markovnikov) product. The scope of this transformation has been investigated using a variety of activated alkenes. Isolation and characterisation of substrate‐coordinated intermediates reveal available coordination sites, which provide insight into the proposed catalytic cycle.magnified image
Highlights
Phosphorus-containing compounds are a precious commodity, finding use in numerous areas such as organocatalysis,[1] bulk and fine chemical production,[2] and the pharmaceutical industry.[3]
Abstract: we report the synthesis of three heteroleptic first-row transition metal(II) complexes containing carbazolido NNN pincer ligands and conversion to the corresponding metal(I)-carbonyl complexes via a reductive carbonylation route
Following our previous report, which detailed the use of low-coordinate transition metal precatalysts in the hydrophosphination of isocyanates,[4] we looked to extend our studies to other unsaturated substrates
Summary
Phosphorus-containing compounds are a precious commodity, finding use in numerous areas such as organocatalysis,[1] bulk and fine chemical production,[2] and the pharmaceutical industry.[3]. Of special interest is the hydrophosphination of olefins and alkynes, which has received much attention in the last two decades.[5,6,7,8,9,10,11] The potential for accessing atomefficient transformations involving regio- and stereoselective processes has, in turn, driven advances for metal-catalysed hydroelementation reactions. This has been revitalised by the development of tailored catalyst design; a core area for regioselective metal-catalysed hydrophosphination (Scheme 1). The quest for cheaper, earth-abundant, non-toxic catalysts for hydrophosphination and other hetero-atom insertion processes, involving iron,[5,6,9,16,17,18,19,20,21,22,23,24,25] cobalt,[26,27,28,29,30,31] and manganese[32] is of continuing importance
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
