Abstract

The lipophilic character of a series of new isoxazolyl-naphthoquinones has been studied. Partition chromatography procedures (RP-HPLC and RP-TLC) were developed for determining the log Po-w(n-octanol/water partition coefficient) values. The experimental values from these methods were validated by comparison with those obtained from the conventional shake flask method, except with the more lipophilic because they have poor water solubility. Also, the log Po-w was calculated using a CLOGP computer programme.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call