Abstract
As traditional barriers are vulnerable to organic solvents or surfactants, a new fluoroalkyl-silica barrier with superior confining ability was developed for paper-based analytical devices (PADs). The as-prepared fluoroalkyl-silica barrier is able to contain surfactant solutions and pure organic solvents even alcohols. Based on the fluoroalkyl-silica barrier, PADs associated with condensing-enrichment effect were explored for Ni(II) assays involving ethanol and bacteria assays including sodium dodecyl sulfate (SDS) and chloroform. The exhibited work has the potential to significantly expand the applications of paper-based microfluidics or assays to include process/analysis involving organic solvents or surfactant solutions.
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