Abstract
The partition of rat erythrocytes in dextran-polyethylene glycol aqueous two-phase systems containing the hydrophobic affinity probe polyethylene glycol-palmitate has been examined. Erythrocytes from rats bearing the subcutaneous Leydig cell tumour F344 showed a significantly reduced top phase partition compared with erythrocytes from non-tumour bearing control rats, indicating a decreased hydrophobicity of the erythrocyte surface that was associated with tumour growth. Cell partition of readily accessible erythrocytes may offer a simple procedure for following the development of certain tumours.
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Schedule a callMore From: Pathobiology : journal of immunopathology, molecular and cellular biology
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