Abstract
Elastomeric polyurethane films containing HDI or IPDI diisocyanate, poly(caprolactone) diol and butane-1,4-diol (BD) or gastrodin (GS) were synthesized in two-step polyaddition reaction. Their chemical structures were confirmed by FTIR and NMR spectroscopy. The phase structure was analyzed by WAXD and DSC methods, confirming the presence of a crystalline phase in the hard domains. The introduction of GS instead of BD results in an increase in the free surface energy of the films (FSE > 40 mJ/m2). The consequence of this is an increase in the water uptake, but at the same time a reduction in resistance to hydrolysis in Baxter's salt solution, as well as increased biodegradability in contact with bacterial strains (Bacillus sp. - gram positive, Pseudomonas sp. - gram negative). PU elastomeric films modified by gastrodin can be applied in tissue engineering films as temporary biomaterials with hydrophilic properties, capable of biodegradation in the body.
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