Hydrophilic platinum complexes of N-2-hydroxyethyl- and N, N-di(2-hydroxyethyl)- N′-benzoylthiourea ligands. Crystal and molecular structure of N, N-di(2-hydroxyethyl)- N′-benzoythiourea

Abstract

The crystal and molecular structure of hydrophilic N, N-di(2-hydroxyethyl)- N′-benzoylthiourea (H 3L 4) has been determined. This ligand coordinates to Pt(II), Pd(II) and Ni(II) in a bidentate manner yielding essentially neutral complexes of the type cis-[Pt(H 2L 4) 2]. By contrast, N-(2-hydroexyethyl)- N′-benzoylthiourea (H 3L 5) behaves like a monodentate thiourea ligand and reacts with Pt(II) to yield a mixture of cis and trans complexes of [Pt(H 3L 5) 2Cl 2]. The ( + )FAB mass spectrum of the latter complexes is also discussed.