Abstract
Hydromorphone for cancer pain.
Highlights
Cancer pain is an important and distressing symptom that tends to increase in frequency and intensity as the cancer advances
This review indicated little difference between hydromorphone and other opioids in terms of analgesic efficacy
Data gathered in this review showed that hydromorphone had a similar effect on participant-reported pain intensity as reported for oxycodone and morphine
Summary
Cancer pain is an important and distressing symptom that tends to increase in frequency and intensity as the cancer advances. Epidemiological studies suggest that approximately 15% of people with cancer pain fail to experience acceptable pain relief with conventional management. Uncontrolled pain can lead to physical and psychological distress and can, have a drastic effect on people’s quality of life. Cancer pain is an important and distressing symptom of the disease, which tends to increase in frequency and intensity as the cancer advances. It has been estimated that 30% to 50% of people with cancer categorise their pain as moderate to severe and that between 75% and 90% of people with cancer experience pain which has a major impact on their daily life (Portenoy 1999).
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