Abstract

The hydrogenation of 2-methylindole to 2-methylindoline in toluene was studied at 60°C and 40bar hydrogen pressure in a batch mode using a range of carbon, alumina, and zeolite supported metal catalysts were performed in toluene. The results were compared with a more conventional catalytic system containing besides 5% Pt/C also 1.2eq. of p-toluenesulfonic acid in ethanol:water (50:50v/v). The highest turnover frequency (TOF) was obtained a zeolite supported iridium catalyst.

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