Abstract
Hydrogen peroxide is the simplest of the peroxides and is used as a chemical intermediate and bleaching agent. As a strong oxidizing agent with high reactivity, hydrogen peroxide can damage cellular macromolecules. In dermal and ocular exposure, hydrogen peroxide is corrosive to the skin and eyes, while inhalational exposure to the vapors can be irritating to the respiratory tract. The management of dermal exposure include removal of the source and washing of the contacted area with water or saline 0.9% for at least 15min. Endotracheal intubation, corticosteroids, and bronchodilator may be needed in inhalational exposure to the vapors of hydrogen peroxide. Ingestion of hydrogen peroxide causes toxicity through three main mechanisms: direct caustic injury, oxygen gas embolization and lipid peroxidation.
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