Abstract
Hydrogen peroxide (H 2O 2) production during phagocytosis was studied in polymorphonuclear leukocytes obtained from children suffering from severe protein-calorie malnutrition. Formation of H 2O 2 was significantly reduced both in the resting condition and during phagocytosis. Improvement in this function of leukocytes was observed following nutritional rehabilitation. Sub-optimal H 2O 2 production during phagocytosis may be one of the reasons for impaired bactericidal activity of leukocytes seen in children with protein-calorie malnutrition.
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Schedule a callMore From: Clinica chimica acta; international journal of clinical chemistry
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