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Abstract
The Na and K flux along the concentration gradients and the active transport of these ions through the neuron membrane of the snailHelix pomatia were investigated as functions of pH of the medium by Conway's method (1, 2) of loading cells with Na ions in the cold followed by restoration of the ionic composition by incubation at room temperature. The pH-maximum of the ion migration rates along concentration gradients was in the acid region for Na flux and in the neutral or weakly alkaline region for K. Hydrogen has an inhibitory effect on active ion transport. Analysis of the results by the Lineweaver-Burk method showed that the inhibition of the K influx is competitive, and that of the Na efflux noncompetitive.
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