Hydrogen-bonding patterns in pyrimethaminium 3-chlorobenzoate

Abstract

In the crystal structure of the title compound, 2,4-diamino-5-(4-chloro­phen­yl)-6-ethyl­pyrimidin-1-ium 3-chloro­benzoate, C12H14ClN4+·C7H4ClO2−, the cation inter­acts with the carboxyl­ate group of the anion through a pair of N—H⋯O hydrogen bonds, forming a cyclic hydrogen-bonded motif [graph-set notation R22(8)]. This motif self-assembles through a complementary DDAA array of quadruple hydrogen bonds. The pyrimethamine cations are paired about inversion centers through N—H⋯N hydrogen bonds involving a pyrimidine N atom and the 4-amino group of the pyrimethamine cations. Concurrent with hydrogen bonding are Cl⋯Cl and sandwich stacking inter­actions.