Hydrogen Bonding and Concurrent Interactions

Abstract

The lecture deals with the various forms of interactions with dominant electrostatic component. It points to dipole/dipole interactions as strong structure determining factor that often accompanies hydrogen bond and halogen bond interactions, and becomes the major structure determi- ning factor when hydrogen bond donor groups are no longer available. It illustrates a combined use of hydrogen bond, halogen bond and dipolar interactions for engineering of reliable layer motifs.