Abstract
Most of the crystallographic analysis that follows from structure determination involves interpretation of the molecular geometry and a working knowledge of a variety of intra- and intermolecular interactions based purely on geometrical considerations (distance and angle cut off criteria). In this paper, a total of fifty-nine structures of cholane derivatives have been chosen for the prediction of their biological activities and hydrogen bonding interaction analysis. Intermolecular interactions of the type X-H…A [X=C,O, N; A=O, Cl, N, Br] in all the structures have been computed and discussed primarily on the basis of distance-angle scatter for better understanding of molecular packing in cholane derivatives. In some structures, bifurcated hydrogen bonds have been observed. Solute-solvent/solvent-solute interactions have also been investigated to understand more complicated processes that occur for biomolecules in aqueous solution.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
