Abstract
This review discusses the recent advances and design principles for dynamic and cell-responsive hydrogels – biomaterials that respond to locally produced stimuli in and around cells or tissues without external influence.
Highlights
A cell, and its niche, represents an instructive symphony of complex interactions, feedback loops, and signals aimed at controlling cellular behavior and function in real time
A. van Blitterswijk the same university in 1982. He has received a number of prestigious international awards including the George Winter award of the European Society for Biomaterials (ESB), the Career Achievement
Researchers have developed understanding of the forces generated by cells in tissue remodeling and cellular functions ranging from cell adhesion, migration, proliferation, differentiation and morphogenesis.[39,40,41,42]
Summary
A cell, and its niche, represents an instructive symphony of complex interactions, feedback loops, and signals aimed at controlling cellular behavior and function in real time. With significant progress in the field of polymer chemistry, synthetic chemistry, and supramolecular chemistry, the capacity to design and tailor polymer architecture and hydrogel networks has advanced.[22,23,24] No longer confined to synthesizing covalent and static networks from conventional radical crosslinking methods, current reports of instructive, stimuli responsive, and biodegradable hydrogels bring closer the realization of complex and dynamic systems that mimic ECM functions. Aligned with these efforts, focus has been shifted to exploring different chemistries to form dynamic hydrogels.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
