Abstract
Incorporation of glycosaminoclycans (GAGs) into biomaterials opens up new routes for the presentation of various bioactive molecules. The review on page 8861 by U. Freudenberg, K. Kiick, C. Werner and co-workers covers recent approaches to GAG-based materials, highlighting modular, tunable biohybrid hydrogels obtained by covalent and non-covalent conjugation schemes, as well as theory-driven design concepts and advanced processing technologies. Examples of the application of the resulting materials in regenerative medicine are provided.
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