Abstract
Almost 2000 different constituents of the human volatilomehave already been reported from numerous individual studies lookingat volatile organic compounds (VOCs) in specific compartments – skin,breath, blood, urine, feces or cell lines. In most cases, the useof VOCs from a single body fluid is sufficient or even preferred.In this chapter we present and discuss a hybrid volatolomic approachthat can inevitably increase the diagnostic value of the targetedapplication. The hybrid approach reviews the existence of VOCs inseveral body fluids and the usefulness of a “hybrid” approach thatcombines their profiles collected from two or more body fluids. Perspectivesof this approach in developing the field of diagnostics to a new levelwill be presented and discussed.
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